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What is the current best evidence available to support your clinical decisions?

MacPLUS FS is designed to find the best evidence-based answer to your clinical questions by simultaneously searching the leading evidence-driven medical publications and high quality clinical literature.

Pyramid of Evidence Diagram
NewEvidence-Based Medicine: An Oral History (video)
NewEvidence-Based history in the making: the first 20 years of the Cochrane Collaboration (video)

These are the most read* articles** we've found across all disciplines.

 1.Major Bleeding and Hemorrhagic Stroke With Direct Oral Anticoagulants in Patients With Renal Failure: Systematic Review and Meta-Analysis of Randomized Trials.
Chest. 2016 Jun;149(6):1516-24. doi: 10.1016/j.chest.2015.12.029. Epub 2016 Jan 18. (Systematic Review)
Read 1548 times
 2.Acupuncture for the prevention of episodic migraine.
Cochrane Database Syst Rev. 2016 Jun 28;(6):CD001218. doi: 10.1002/14651858.CD001218.pub3. (Systematic Review)
Read 1458 times
 3.2016 updated EULAR evidence-based recommendations for the management of gout.
Ann Rheum Dis. 2016 Jul 25. pii: annrheumdis-2016-209707. doi: 10.1136/annrheumdis-2016-209707. (Systematic Review)
Read 1292 times

* by physicians around the world in the past 30 days
** excluding articles with relevance or newsworthiness scores below 6 (on a scale of 1 to 7)