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What is the current best evidence available to support your clinical decisions?

MacPLUS FS is designed to find the best evidence-based answer to your clinical questions by simultaneously searching the leading evidence-driven medical publications and high quality clinical literature.

Pyramid of Evidence Diagram
NewEvidence-Based Medicine: An Oral History (video)
NewEvidence-Based history in the making: the first 20 years of the Cochrane Collaboration (video)

These are the most read* articles** we've found across all disciplines.

 1.Beta-blockers for hypertension.
Cochrane Database Syst Rev. 2017 Jan 20;1:CD002003. doi: 10.1002/14651858.CD002003.pub5. (Systematic Review)
Read 4093 times
 2.Clinical Outcomes of Metformin Use in Populations With Chronic Kidney Disease, Congestive Heart Failure, or Chronic Liver Disease: A Systematic Review.
Ann Intern Med. 2017 Feb 7;166(3):191-200. doi: 10.7326/M16-1901. Epub 2017 Jan 3. (Systematic Review)
Read 2383 times
 3.Causes of Death in Anticoagulated Patients With Atrial Fibrillation.
J Am Coll Cardiol. 2016 Dec 13;68(23):2508-2521. doi: 10.1016/j.jacc.2016.09.944. (Systematic Review)
Read 1633 times

* by physicians around the world in the past 30 days
** excluding articles with relevance or newsworthiness scores below 6 (on a scale of 1 to 7)