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What is the current best evidence available to support your clinical decisions?

MacPLUS FS is designed to find the best evidence-based answer to your clinical questions by simultaneously searching the leading evidence-driven medical publications and high quality clinical literature.

Pyramid of Evidence Diagram
NewEvidence-Based Medicine: An Oral History (video)
NewEvidence-Based history in the making: the first 20 years of the Cochrane Collaboration (video)

These are the most read* articles** we've found across all disciplines.

 1.Diabetes Medications for Adults With Type 2 Diabetes: An Update
Rockville (MD): Agency for Healthcare Research and Quality (US); 2016 Apr. No. 16-EHC013-EF (Systematic Review)
Read 1706 times
 2.Antibiotics Versus Appendicectomy for the Treatment of Uncomplicated Acute Appendicitis: An Updated Meta-Analysis of Randomised Controlled Trials.
World J Surg. 2016 May 19. (Systematic Review)
Read 1571 times
 3.Prescription of Long-Acting Opioids and Mortality in Patients With Chronic Noncancer Pain.
JAMA. 2016 Jun 14;315(22):2415-23. doi: 10.1001/jama.2016.7789. (Original Study)
Read 1395 times

* by physicians around the world in the past 30 days
** excluding articles with relevance or newsworthiness scores below 6 (on a scale of 1 to 7)