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What is the current best evidence available to support your clinical decisions?

MacPLUS FS is designed to find the best evidence-based answer to your clinical questions by simultaneously searching the leading evidence-driven medical publications and high quality clinical literature.

Pyramid of Evidence Diagram
NewEvidence-Based Medicine: An Oral History (video)
NewEvidence-Based history in the making: the first 20 years of the Cochrane Collaboration (video)

These are the most read* articles** we've found across all disciplines.

 1.Sodium-glucose cotransporter 2 inhibitors and risk of adverse renal outcomes among type 2 diabetes patients: a network and cumulative meta-analysis of randomized controlled trials.
Diabetes Obes Metab. 2017 Feb 27. doi: 10.1111/dom.12917. (Systematic Review)
Read 1136 times
 2.Rivaroxaban or Aspirin for Extended Treatment of Venous Thromboembolism.
N Engl J Med. 2017 Mar 30;376(13):1211-1222. doi: 10.1056/NEJMoa1700518. Epub 2017 Mar 18. (Original Study)
Read 1028 times
 3.Interventions To prevent age-related cognitive decline, mild cognitive impairment, and clinical Alzheimer’s-type dementia. Comparative Effectiveness Review No. 188.
AHRQ Comparative Effectiveness Reviews. 2017 Mar. No. 189;1-693. (Systematic Review)
Read 1018 times

* by physicians around the world in the past 30 days
** excluding articles with relevance or newsworthiness scores below 6 (on a scale of 1 to 7)