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What is the current best evidence available to support your clinical decisions?

MacPLUS FS is designed to find the best evidence-based answer to your clinical questions by simultaneously searching the leading evidence-driven medical publications and high quality clinical literature.

Pyramid of Evidence Diagram
NewEvidence-Based Medicine: An Oral History (video)
NewEvidence-Based history in the making: the first 20 years of the Cochrane Collaboration (video)

These are the most read* articles** we've found across all disciplines.

 1.Aspirin for primary prevention of cardiovascular and all-cause mortality events in diabetes: updated meta-analysis of randomized controlled trials.
Diabet Med. 2016 Apr 17. doi: 10.1111/dme.13133. (Systematic Review)
Read 2185 times
 2.Major bleeding risk among non-valvular atrial fibrillation patients initiated on apixaban, dabigatran, rivaroxaban or warfarin: a ``real-world`` observational study in the United States.
Int J Clin Pract. 2016 Sep;70(9):752-63. doi: 10.1111/ijcp.12863. Epub 2016 Aug 23. (Original Study)
Read 1562 times
 3.CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea.
N Engl J Med. 2016 Sep 8;375(10):919-31. doi: 10.1056/NEJMoa1606599. Epub 2016 Aug 28. (Original Study)
Read 1543 times

* by physicians around the world in the past 30 days
** excluding articles with relevance or newsworthiness scores below 6 (on a scale of 1 to 7)