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Welcome to Pain PLUS - "one-stop" access to pre-appraised evidence to support your clinical decisions.

Pain PLUS was developed as part of a research study funded by the Canadian Institutes of Health Research (CIHR).

Powered by the Health Knowledge Refinery Health Knowledge Refinery, McMaster PLUS is a division within the McMaster HKR that includes the process of having articles critically appraised through the Critical Appraisal Process (CAP) to identify those that are methodologically sound, and then having pass articles rated by clinicians for relevance and newsworthiness through the McMaster Online Rating of Evidence (MORE) system (see McMaster PLUS for a complete description of the critical appraisal and rating processes).

Pain PLUS provides a new path to address the key question in this era of evidence-based medicine: what is the current best evidence available to support clinical decisions?

These are the most read* articles** we've found across all disciplines.
 1.The magnitude of nocebo effects in pain: A meta-analysis.
Pain. 2014 Apr 26. pii: S0304-3959(14)00195-X. doi: 10.1016/j.pain.2014.04.016. (Review)
 2.Corticosteroids as standalone or add-on treatment for sore throat.
Cochrane Database Syst Rev. 2012 Oct 17;10:CD008268. doi: 10.1002/14651858.CD008268.pub2. (Review)
 3.What is the value of the routine use of patient-reported outcome measures toward improvement of patient outcomes, processes of care, and health service outcomes in cancer care? A systematic review of controlled trials.
J Clin Oncol. 2014 May 10;32(14):1480-501. doi: 10.1200/JCO.2013.53.5948. Epub 2014 Apr 7. (Review)

* by users around the world in the past 30 days
** excluding articles with relevance or newsworthiness scores below 6