COVID-19 Evidence Alerts
from McMaster PLUSTM

Current best evidence for clinical care (more info)

Prognosis Teles Abrao Trad A, Ibirogba ER, Elrefaei A, et al. Complications and outcomes of SARS-CoV-2 in pregnancy: where and what is the evidence? Hypertens Pregnancy. 2020 Aug;39(3):361-369. doi: 10.1080/10641955.2020.1769645. Epub 2020 May 26.

OBJECTIVES: To add to the growing evidence on SARS-CoV-2 infection during pregnancy, so as to better inform clinical decision making and optimize patient outcomes.

METHODS: A systematic search of relevant databases was perfomed on 25 March 2020 and a repeat search, on 10 April 2020. Reports of pregnant patients with SARS-CoV-2 infection at any time during their pregnancy were reviewed and summarized .

RESULTS: We summarized the outcomes of a total of 155 pregnant women and 118 neonates. The evidence suggests a similar rate of severe COVID-19 cases in pregnant women and the general population. The frequency of cesarean deliveries is high, against guidelines recommendations.

CONCLUSION: Limited data on COVID-19 during preganacy, associated with a wide variation in the methodology make accurate data interpretation difficult.

Discipline / Specialty Area Score
Intensivist/Critical Care
Public Health
Pediatric Neonatology
Family Medicine (FM)/General Practice (GP)
Infectious Disease
Comments from MORE raters

Intensivist/Critical Care rater

Data on Sars-CoV-2 infected pregnant women are increasingly available in the medical literature and provide relevant information to the scientific community.