COVID-19

COVID-19 Evidence Alerts
from McMaster PLUSTM

Current best evidence for clinical care (more info)

Treatment Qaseem A, Yost J, Etxeandia-Ikobaltzeta I, et al. Should Remdesivir Be Used for the Treatment of Patients With COVID-19? Rapid, Living Practice Points From the American College of Physicians (Version 2). Ann Intern Med. 2021 May;174(5):673-679. doi: 10.7326/M20-8101. Epub 2021 Feb 9.
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Abstract

Clinicians must have access to the best available evidence to inform point-of-care decisions about the use of remdesivir in patients with COVID-19. This article provides updated advice from the American College of Physicians for clinicians based on an updated rapid review.

Ratings
Discipline / Specialty Area Score
Infectious Disease
Intensivist/Critical Care
Respirology/Pulmonology
Hospital Doctor/Hospitalists
Internal Medicine
Comments from MORE raters

Internal Medicine rater

It is good to have more data on this. The Solidarity trial, which was the largest trial, didn't show any difference in mortality. For hospitalized patients requiring supplemental oxygen, dexamethasone +/- remdesivir is the way to go.