COVID-19

COVID-19 Evidence Alerts
from McMaster PLUSTM

Current best evidence for clinical care (more info)

Diagnosis Shah MM, Salvatore PP, Ford L, et al. Performance of Repeat BinaxNOW Severe Acute Respiratory Syndrome Coronavirus 2 Antigen Testing in a Community Setting, Wisconsin, November 2020-December 2020. Clin Infect Dis. 2021 Jul 15;73(Suppl 1):S54-S57. doi: 10.1093/cid/ciab309.
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Abstract

Repeating the BinaxNOW antigen test for severe acute respiratory syndrome coronavirus 2 using 2 groups of readers within 30 minutes resulted in high concordance (98.9%) in 2110 encounters. Same-day repeat antigen testing did not significantly improve test sensitivity (77.2% to 81.4%) while specificity remained high (99.6%).

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Discipline / Specialty Area Score
Public Health
Infectious Disease
Comments from MORE raters

Infectious Disease rater

This type of article reminds doctors that entering an order for a test does not grant that the test will be what is ordered. I believe it is worth letting the readers know that there are different algorithms to reach the diagnosis of SARS-CoV-2 infection.