Diagnostic value and key features of computed tomography in Coronavirus Disease 2019

Emerg Microbes Infect. 2020 Dec;9(1):787-793. doi: 10.1080/22221751.2020.1750307.

Abstract

On 31 December 2019, a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, Hubei province, China, and caused the outbreak of the Coronavirus Disease 2019 (COVID-19). To date, computed tomography (CT) findings have been recommended as major evidence for the clinical diagnosis of COVID-19 in Hubei, China. This review focuses on the imaging characteristics and changes throughout the disease course in patients with COVID-19 in order to provide some help for clinicians. Typical CT findings included bilateral ground-glass opacity, pulmonary consolidation, and prominent distribution in the posterior and peripheral parts of the lungs. This review also provides a comparison between COVID-19 and other diseases that have similar CT findings. Since most patients with COVID-19 infection share typical imaging features, radiological examinations have an irreplaceable role in screening, diagnosis and monitoring treatment effects in clinical practice.

Keywords: Coronavirus Disease 2019; SARS-CoV-2; computed tomography; diagnosis; ground-glass opacity.

Publication types

  • Review

MeSH terms

  • Betacoronavirus
  • COVID-19
  • COVID-19 Testing
  • Clinical Laboratory Techniques
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / diagnostic imaging*
  • Diagnosis, Differential
  • Disease Progression
  • Humans
  • Lung* / diagnostic imaging
  • Lung* / pathology
  • Nucleic Acid Amplification Techniques
  • Pandemics
  • Pneumonia, Viral / diagnostic imaging*
  • Radiography, Thoracic
  • SARS-CoV-2
  • Severe Acute Respiratory Syndrome / diagnostic imaging
  • Tomography, X-Ray Computed*