Coronavirus Diseases (COVID-19) Current Status and Future Perspectives: A Narrative Review

Int J Environ Res Public Health. 2020 Apr 14;17(8):2690. doi: 10.3390/ijerph17082690.

Abstract

At the end of 2019 a novel virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing severe acute respiratory syndrome expanded globally from Wuhan, China. In March 2020 the World Health Organization declared the SARS-Cov-2 virus a global pandemic. We performed a narrative review to describe existing literature with regard to Corona Virus Disease 2019 (COVID-19) epidemiology, pathophysiology, diagnosis, management and future perspective. MEDLINE, EMBASE and Scopus databases were searched for relevant articles. Although only when the pandemic ends it will be possible to assess the full health, social and economic impact of this global disaster, this review represents a picture of the current state of the art. In particular, we focus on public health impact, pathophysiology and clinical manifestations, diagnosis, case management, emergency response and preparedness.

Keywords: COVID-19; coronavirus; emergency; pandemic; pathogenesis; preparedness.

Publication types

  • Review

MeSH terms

  • Betacoronavirus
  • COVID-19
  • China / epidemiology
  • Coronavirus Infections* / diagnosis
  • Coronavirus Infections* / drug therapy
  • Coronavirus Infections* / epidemiology
  • Coronavirus Infections* / physiopathology
  • Coronavirus Infections* / therapy
  • Coronavirus*
  • Disease Outbreaks / prevention & control*
  • Humans
  • Nasopharynx / virology
  • Pandemics / prevention & control*
  • Pneumonia, Viral* / diagnosis
  • Pneumonia, Viral* / drug therapy
  • Pneumonia, Viral* / epidemiology
  • Pneumonia, Viral* / physiopathology
  • Pneumonia, Viral* / therapy
  • Pneumonia, Viral* / virology
  • Polymerase Chain Reaction
  • Predictive Value of Tests
  • Public Health
  • SARS-CoV-2
  • Severe Acute Respiratory Syndrome / epidemiology
  • Severe Acute Respiratory Syndrome / virology
  • World Health Organization