Clinical characteristics of 54 medical staff with COVID-19: A retrospective study in a single center in Wuhan, China

J Med Virol. 2020 Jul;92(7):807-813. doi: 10.1002/jmv.25793. Epub 2020 Apr 6.

Abstract

In December 2019, an outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) infection occurred in Wuhan, and rapidly spread to worldwide, which has attracted many people's concerns about the patients. However, studies on the infection status of medical personnel is still lacking. A total of 54 cases of SARS-Cov-2 infected medical staff from Tongji Hospital between 7 January and 11 February 2020 were analyzed in this retrospective study. Clinical and epidemiological characteristics were compared between different groups by statistical method. From 7 January to 11 February 2020, 54 medical staff of Tongji Hospital were hospitalized due to coronavirus disease 2019 (COVID-19). Most of them were from other clinical departments (72.2%) rather than emergency department (3.7%) or medical technology departments (18.5%). Among the 54 patients with COVID-19, the distribution of age had a significant difference between non-severe type and severe/critical cases (median age: 47 years vs 38 years; P = .0015). However, there was no statistical difference in terms of gender distribution and the first symptoms between theses two groups. Furthermore, we observed that the lesion regions in SARS-Cov-2 infected lungs with severe-/critical-type of medical staff were more likely to exhibit lesions in the right upper lobe (31.7% vs 0%; P = .028) and right lung (61% vs 18.2%; P = .012). Based on our findings with medical staff infection data, we suggest training for all hospital staff to prevent infection and preparation of sufficient protection and disinfection materials.

Keywords: COVID-19 patients; SARS-Cov-2; medical staff; nucleic acid-negative; nucleic acid-positive.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Antiviral Agents / therapeutic use
  • Betacoronavirus / drug effects
  • Betacoronavirus / pathogenicity*
  • COVID-19
  • China
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / drug therapy
  • Coronavirus Infections / physiopathology*
  • Coronavirus Infections / transmission*
  • Female
  • Hospital Departments / classification
  • Humans
  • Immunoglobulins / therapeutic use
  • Infectious Disease Transmission, Patient-to-Professional / classification*
  • Interferons / therapeutic use
  • Male
  • Medical Staff, Hospital
  • Middle Aged
  • Pandemics
  • Pneumonia, Viral / diagnosis
  • Pneumonia, Viral / drug therapy
  • Pneumonia, Viral / physiopathology*
  • Pneumonia, Viral / transmission*
  • Retrospective Studies
  • SARS-CoV-2
  • Severity of Illness Index
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Antiviral Agents
  • Immunoglobulins
  • Interferons