Aim: To examine the literature on Traditional Chinese Medicine (TCM) used in the treatment, prevention and supportive care in patients with COVID-19.
Design: A narrative review was performed.
Data sources: A systematic and comprehensive search was conducted on both Chinese and English electronic databases: China National Knowledge Infrastructure, Wanfang Data, CINAHL, Embase, Cochrane, PubMed, PsycINFO. Articles published from 1 December 2019 -1 April 2020 were included in this review.
Review methods: Studies reporting on the treatment and prevention of COVID-19 using TCM regardless of study designs were included. In addition, grey literatures, including media reports on Chinese government websites or official media websites and treatment guidelines were searched for TCM treatment and prevention on COVID-19.
Results: Limited research has been published on the use of TCM for COVID-19. We qualitatively described and synthesized the published research and current clinical practice on the use of TCM for COVID-19, and focused on the following areas: TCM treatment used in SARS, MERS, H1N1; TCM treatment plan for COVID-19; TCM in Prevention and Treatment at Early Stage of COVID-19; TCM emotional therapy; and personalized TCM treatment plan.
Conclusion: The combination of western medicine and TCM in treatment, and treatment based on the local condition, isolation, personal protective measures are of great significance for the prevention and treatment of COVID-19. Relevant laboratory research and clinical evaluation should be continued to collect scientific evidences on the efficacy of TCM.
Impact: TCM has been used in the treatment and prevention of COVID-19 in China, and the clinical evidences indicated that TCM regulates immunity and exerts anti-viral effect simultaneously. This review provides practical recommendation for the policymakers in the selection process of the treatment and preventive measures for the global pandemic of COVID-19.
目的: 研究关于中医 (TCM) 在新冠肺炎患者的治疗、预防和支持性护理中应用的文献。 设计: 开展叙述性评估。 数据来源: 对中英文电子数据库 (中国知识基础设施工程、万方数据、CINAHL、Embase、Cochrane、PubMed、PsycINFO) 进行了系统化全面检索。2019年12月1日至2020年4月1日发表的文章被纳入本项评估。 评估方法: 无论研究设计如何, 均纳入了报道运用中医治疗和预防新冠肺炎的研究。此外, 还检索了灰色文献, 包括中国政府网站或官方媒体网站的媒体报道和治疗指南, 以了解中医在治疗和预防新冠肺炎方面的情况。 结果: 关于中医在新冠肺炎方面的应用, 目前已发表的研究数量有限。我们对已发表的关于中医在新冠肺炎中应用的研究和目前的临床实践进行了定性说明和综合, 并重点关注以下几个方面: 中医治疗在SARS、MERS、H1N1中的应用; 新冠肺炎的中医治疗方案; 中医在新冠肺炎早期防治中的应用; 中医情感治疗; 个性化中医治疗方案。 结论: 中西医结合治疗, 以及基于当地情况、隔离、个人防护措施采取的治疗, 对防治新冠肺炎具有重要意义。应继续开展相关的实验室研究和临床评价, 为中医疗效提供科学依据。 影响: 在中国, 中医已用于防治新冠肺炎, 且临床证据表明, 中医在调节机体免疫力的同时, 也发挥了抗病毒作用。本项评估为决策者在选择新冠肺炎全球大流行病的治疗和预防措施时提供了切实可行的建议。.
Keywords: Chinese herbs; TCM emotional therapy; TCM prevention for COVID-19; TCM treatment for COVID-19; complementary therapy; coronavirus; narrative review; nurses/midwives/nursing; personalized TCM treatment; traditional chinese medicine.
© 2020 John Wiley & Sons Ltd.