Abstract
A short-cut review of the available medical literature was carried out to establish whether remdesivir was an effective treatment for patients with confirmed COVID-19 infection. After abstract review, five papers were found to answer this clinical question using the detailed search strategy. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. It is concluded that despite some recent promising studies, further well-designed and larger trials are needed to answer this specific question.
Keywords:
emergency care systems.
© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.
MeSH terms
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Adenosine Monophosphate / administration & dosage
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Adenosine Monophosphate / adverse effects
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Adenosine Monophosphate / analogs & derivatives*
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Adult
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Alanine / administration & dosage
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Alanine / adverse effects
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Alanine / analogs & derivatives*
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Antiviral Agents / administration & dosage
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Antiviral Agents / adverse effects
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Betacoronavirus* / drug effects
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Betacoronavirus* / isolation & purification
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COVID-19
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COVID-19 Drug Treatment
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Clinical Trials as Topic
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Coronavirus Infections* / diagnosis
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Coronavirus Infections* / drug therapy
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Coronavirus Infections* / physiopathology
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Evidence-Based Practice
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Female
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Humans
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Male
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Pandemics*
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Pneumonia, Viral* / diagnosis
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Pneumonia, Viral* / drug therapy
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Pneumonia, Viral* / etiology
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Pneumonia, Viral* / physiopathology
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SARS-CoV-2
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Treatment Outcome
Substances
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Antiviral Agents
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remdesivir
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Adenosine Monophosphate
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Alanine