In AF, the effects of DOACs vs. warfarin on death and stroke/systemic embolism vary by baseline CrCl level

Ann Intern Med. 2023 Aug;176(8):JC91. doi: 10.7326/J23-0054. Epub 2023 Aug 1.

Abstract

Harrington J, Carnicelli AP, Hua K, et al. Direct oral anticoagulants versus warfarin across the spectrum of kidney function: patient-level network meta-analyses from COMBINE AF. Circulation. 2023;147:1748-1757. 37042255.

Publication types

  • Comment

MeSH terms

  • Administration, Oral
  • Anticoagulants / adverse effects
  • Atrial Fibrillation* / complications
  • Atrial Fibrillation* / drug therapy
  • Embolism*
  • Humans
  • Stroke*
  • Warfarin / adverse effects

Substances

  • Anticoagulants
  • Warfarin