Guidance for the treatment and prevention of obstetric-associated venous thromboembolism

J Thromb Thrombolysis. 2016 Jan;41(1):92-128. doi: 10.1007/s11239-015-1309-0.

Abstract

Venous thromboembolism (VTE), which may manifest as pulmonary embolism (PE) or deep vein thrombosis (DVT), is a serious and potentially fatal condition. Treatment and prevention of obstetric-related VTE is complicated by the need to consider fetal, as well as maternal, wellbeing when making management decisions. Although absolute VTE rates in this population are low, obstetric-associated VTE is an important cause of maternal morbidity and mortality. This manuscript, initiated by the Anticoagulation Forum, provides practical clinical guidance on the prevention and treatment of obstetric-associated VTE based on existing guidelines and consensus expert opinion based on available literature where guidelines are lacking.

Keywords: Anticoagulants; Deep vein thrombosis; Obstetric; Pregnancy; Prophylaxis; Pulmonary embolism; Venous thromboembolism.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Female
  • Humans
  • Practice Guidelines as Topic
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / mortality
  • Pregnancy Complications, Cardiovascular / prevention & control*
  • Venous Thromboembolism / mortality
  • Venous Thromboembolism / prevention & control*
  • Venous Thrombosis / mortality
  • Venous Thrombosis / prevention & control*