High sensitivity and specificity of an automated IgG-specific chemiluminescence immunoassay for diagnosis of HIT

Blood. 2018 Sep 20;132(12):1345-1349. doi: 10.1182/blood-2018-04-847483. Epub 2018 Jul 31.

Authors

Theodore E Warkentin^{1

2

3}, Jo-Ann I Sheppard¹, Lori-Ann Linkins^{2

4}, Donald M Arnold^{2

3}, Ishac Nazy^{2

3}

Affiliations

¹ Department of Pathology and Molecular Medicine and.
² Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
³ McMaster Centre for Transfusion Research, Hamilton, ON, Canada; and.
⁴ Thrombosis and Atherosclerosis Research Institute, Hamilton, ON, Canada.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Aged, 80 and over
Anticoagulants / adverse effects*
Anticoagulants / immunology
Bayes Theorem
Female
Heparin / adverse effects*
Heparin / immunology
Humans
Immunoassay / methods
Immunoglobulin G / blood*
Immunoglobulin G / immunology
Luminescent Measurements / methods*
Male
Middle Aged
Platelet Factor 4 / immunology
Thrombocytopenia / blood
Thrombocytopenia / chemically induced*
Thrombocytopenia / diagnosis*
Thrombocytopenia / immunology

Substances

Anticoagulants
Immunoglobulin G
Platelet Factor 4
Heparin