Studying the effect of stent thickness and porosity on post-stent implantation hemodynamics

J Med Eng Technol. 2021 Jul;45(5):408-416. doi: 10.1080/03091902.2021.1912204. Epub 2021 May 4.

Abstract

This study investigates the effect of stent thickness and stent porosity which are important factors determining the post-treatment intra-aneurysmal hemodynamics. The study uses computational fluid dynamics (CFD) to estimate the hemodynamic behaviour: flow velocity, pressure distributions, time-averaged wall shear stress (TAWSS), oscillatory shear index (OSI), besides relative residence time (RRT) blood flow distribution in a proposed stent and three other commercially available stents. The hemodynamic behaviour is compared between four different cases. In each case, each stent has the specific thickness and porosity values. The results show that the velocity magnitude inside the sac declined in thinner stents and lower porosity stents, TAWSS on the aneurysmal wall declined linearly in lower porosity stents, OSI and RRT increased obviously in thicker stents and higher porosity stents. Finally, the results conclude that the stent with the lowest thickness and porosity has the best performance that leads to post-stent thrombus formation and healing. However, the proposed stent design, a more porous construct, has a higher RRT compared to the used commercially available stents, which helps promote the thrombus growth inside the aneurysm sac.

Keywords: Stent thickness and porosity; hemodynamics; cerebral aneurysm; computational fluid dynamics (CFD); thrombosis formation.

MeSH terms

  • Computer Simulation
  • Hemodynamics*
  • Models, Cardiovascular
  • Porosity
  • Stents*
  • Stress, Mechanical