1 Department of Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada; Department of Obstetrics and Gynaecology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada; ICES, Toronto, Ontario, Canada. Electronic address: rayj@smh.ca.
2 Department of Pathology and Molecular Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.