Overview of Therapeutic Approaches for Cholesterol Lowering and Attenuation of Thrombosis for Prevention of Atherothrombosis

Circ Res. 2019 Feb;124(3):351-353. doi: 10.1161/CIRCRESAHA.118.314576.

Authors

Jeffrey I Weitz¹, Sergio Fazio²

Affiliations

¹ From the Department of Medicine, Department of Biochemistry and Biomedical Sciences, McMaster University, and the Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada (J.I.W.).
² Knight Cardiovascular Institute, Center for Preventive Cardiology, Oregon Health and Science University, Portland (S.F.).

PMID: 30702992
DOI: 10.1161/CIRCRESAHA.118.314576

No abstract available

Keywords: Editorials; atherothrombosis; cholesterol; collagen; fibrinogen; plasminogen; thrombosis.

Publication types

Editorial
Introductory Journal Article
Research Support, Non-U.S. Gov't

MeSH terms

Anticholesteremic Agents / therapeutic use*
Aspirin / adverse effects
Aspirin / therapeutic use
Cholesterol, LDL / blood
Ezetimibe / therapeutic use
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use
Hypercholesterolemia / complications
Hypercholesterolemia / drug therapy*
PCSK9 Inhibitors
Plaque, Atherosclerotic / complications
Plaque, Atherosclerotic / prevention & control*
Rivaroxaban / adverse effects
Rivaroxaban / therapeutic use
Thrombosis / etiology
Thrombosis / prevention & control*

Substances

Anticholesteremic Agents
Cholesterol, LDL
Hydroxymethylglutaryl-CoA Reductase Inhibitors
PCSK9 Inhibitors
Rivaroxaban
PCSK9 protein, human
Ezetimibe
Aspirin