Health-Related Quality of Life of Patients Presenting to the Emergency Department with a Musculoskeletal Disorder

Clinicoecon Outcomes Res. 2022 Feb 19:14:91-103. doi: 10.2147/CEOR.S348138. eCollection 2022.

Abstract

Background: Musculoskeletal disorders (MSKDs) are among the most disabling and costly non-fatal health conditions. They may lead to long-term consequences such as chronic pain, physical limitations, and poorer quality of life. They also account for a significant proportion of emergency department visits, representing between 18% and 25% of all visits, depending on country.

Purpose: To assess the health-related quality of life of patients presenting to the emergency department with a MSKD, to convert their answers to utility scores and to explore the association between diverse socio-demographic and clinical variables and patients' health-related quality of life.

Patients and methods: This is an analysis of cross-sectional data obtained during the baseline assessment performed as part of a 6-month pragmatic randomized controlled trial conducted in an academic emergency department. We included patients aged 18-80 years with a minor MSKD. The main outcome measures were health-related quality of life (five dimensions: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression) and utility scores (-0.148 - worse than death, 0 - dead, 0.949 - perfect health) measured with the EQ-5D-5L. Possible associations were explored by comparing scores across subgroups based on certain socio-demographic (eg, age, gender, triage score) and clinical factors (eg, pain interference on function, pain intensity) and with reference values using descriptive statistics (mean, median), rankFD ANOVAs, and χ 2 tests.

Results: Sixty-nine participants completed the EQ-5D-5L. Mean and median utility scores were, respectively, 0.536 (95% CI: 0.479-0.594) and 0.531 (IQR: 0.356-0.760). Participants with higher levels of pain (<4/10: 0.741, 95% CI: 0.501-0.980; 4-7/10: 0.572, 0.500-0.644; >7/10: 0.433, 0.347-0.518) or pain interference on function (<4/10: 0.685, 95% CI: 0.605-0.764; 4-7/10: 0.463, 0.394-0.533; >7/10: 0.294, 0.126-0.463) presented significantly lower utility scores. No significant differences were found for other socio-demographic characteristics.

Conclusion: In patients with MSKDs who present to the emergency department, higher levels of pain or pain interference are associated with decreased health-related quality of life. These findings need to be confirmed on a larger scale.

Keywords: EQ-5D-5L; emergency services; musculoskeletal disorders; pain; quality of life.

Grants and funding

This research was funded by the CHU de Québec – Université Laval, subsidies from L.J.H. and K.P. and a research grant awarded by the Fondation du CHU de Québec for the multidisciplinary council of the CHU de Québec – Université Laval. R.G. received scholarships from the Canadian Institutes of Health Research, the Cirris, the Ordre professionnel de la physiothérapie du Québec and the Department of Rehabilitation funds of the Faculty of Medicine at Université Laval. K.P. and J.R.G. are Fonds de recherche du Québec-Santé (FRSQ) Junior 1 Research Scholars.