Outcomes of unilateral cataract surgery in children 2-7 years of age: a comparison to surgery in toddlers and infants

J AAPOS. 2022 Aug;26(4):169.e1-169.e5. doi: 10.1016/j.jaapos.2022.03.011. Epub 2022 Jul 19.

Abstract

Purpose: To compare outcomes of unilateral cataract surgery in children aged 2-7 years with the outcomes reported in younger children.

Methods: The medical records of patients who underwent unilateral cataract surgery between the ages of 2-7 years were reviewed retrospectively. Traumatic cataracts and ectopia lentis were excluded. Outcomes were compared to those of the Infant Aphakia Treatment Study (IATS) for infants up to 7 months of age and the Toddler Aphakia and Pseudophakia Study (TAPS) for toddlers between 7-24 months of age who underwent unilateral cataract surgery.

Results: A total of 68 children were included, with a mean follow-up of 4.3 years. The proportion of intraoperative complications (7%) was significantly lower than that reported in IATS but not significantly different from that of TAPS. In our older cohort, more children (41%) had visual acuity better than 20/40 compared to infants (23% [P < 0.05]) and toddlers (11% [P < 0.001]), with a final median visual acuity of 20/44. The proportion of adverse events in our older cohort was reduced (7%) compared to that of infants (81%) and toddlers (24%). Additional unplanned intraocular surgeries occurred less often (6%) than in the infant cohort (72%). No patients developed glaucoma.

Conclusions: Cataract surgery in slightly older children carries less risk of vision-threatening complications and adverse events compared to infants and results in better visual outcomes than in toddlers. Once the decision is made to pursue surgery on a visually significant cataract, the age of the child should determine which relevant risks are emphasized in the informed consent discussion.

MeSH terms

  • Adolescent
  • Aphakia, Postcataract* / surgery
  • Cataract Extraction* / methods
  • Cataract* / etiology
  • Child
  • Child, Preschool
  • Follow-Up Studies
  • Humans
  • Infant
  • Lens Implantation, Intraocular / methods
  • Pseudophakia
  • Retrospective Studies