Since February 2022, Malawi has experienced a cholera outbreak of >54,000 cases. We investigated 6 cases in South Africa and found that isolates linked to the outbreak were Vibrio cholerae O1 serotype Ogawa from seventh pandemic El Tor sublineage AFR15, indicating a new introduction of cholera into Africa from south Asia.
Keywords: Malawi; South Africa; Vibrio cholerae; Vibrio cholerae serogroup O1; bacteria; cholera; enteric infections; sequence type 69.