COVID-19 Evidence Alerts
from McMaster PLUSTM

Current best evidence for clinical care (more info)

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Diagnosis Pilarowski G, Marquez C, Rubio L, et al. Field performance and public health response using the BinaxNOW TM Rapid SARS-CoV-2 antigen detection assay during community-based testing. Clin Infect Dis. 2020 Dec 26. pii: 6052342. doi: 10.1093/cid/ciaa1890.

Among 3,302 persons tested for SARS-CoV-2 by BinaxNOW TM and RT-PCR in a community setting, rapid assay sensitivity was 100%/98.5%/89% using RT-PCR Ct thresholds of 30, 35 and none. The specificity was 99.9%. Performance was high across ages and those with and without symptoms. Rapid resulting permitted immediate public health action.

Discipline / Specialty Area Score
Pediatrics (General)
Public Health
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Infectious Disease
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Comments from MORE raters

Pediatrics (General) rater

Having data to confirm the test works equally well in children is important, but note the very limited numbers in children under 13 years of age.