COVID-19 Evidence Alerts
from McMaster PLUS^TM

Among 3302 persons tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by BinaxNOWTM and reverse transcription polymerase chain reaction (RT-PCR) in a community setting, rapid assay sensitivity was 100%/98.5%/89% using RT-PCR cycle thresholds of 30, 35, and no threshold. The specificity was 99.9%. Performance was high across ages and those with and without symptoms. Rapid resulting permitted immediate public health action.

Pediatrics (General) rater

Having data to confirm the test works equally well in children is important, but note the very limited numbers in children under 13 years of age.

Public Health rater

I will use BinaxNow TM rapid. This paper answered any question I had.