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What is the current best evidence available to support your clinical decisions?

helsebiblioteket | McMaster PLUS is designed to find the best evidence-based answer to your clinical questions by simultaneously searching the leading evidence-driven medical publications and high quality clinical literature.

Pyramid of Evidence Diagram

These are the most read* articles** we've found across all disciplines.

 1.Efficacy of Low-Dose Amitriptyline for Chronic Low Back Pain: A Randomized Clinical Trial.
JAMA Intern Med. 2018 Nov 1;178(11):1474-1481. doi: 10.1001/jamainternmed.2018.4222. (Original Study)
Read 3508 times
 2.Cannabis and cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis of controlled and observational studies.
Pain. 2018 Oct;159(10):1932-1954. doi: 10.1097/j.pain.0000000000001293. (Systematic Review)
Read 2994 times
 3.Association of Thyroid Hormone Therapy With Quality of Life and Thyroid-Related Symptoms in Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-analysis.
JAMA. 2018 Oct 2;320(13):1349-1359. doi: 10.1001/jama.2018.13770. (Systematic Review)
Read 2267 times

* by physicians around the world in the past 30 days
** excluding articles with relevance or newsworthiness scores below 6 (on a scale of 1 to 7)