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What is the current best evidence available to support your clinical decisions?

helsebiblioteket | McMaster PLUS is designed to find the best evidence-based answer to your clinical questions by simultaneously searching the leading evidence-driven medical publications and high quality clinical literature.

Pyramid of Evidence Diagram

These are the most read* articles** we've found across all disciplines.

 1.Effects of aspirin on risks of vascular events and cancer according to bodyweight and dose: analysis of individual patient data from randomised trials.
Lancet. 2018 Jul 12. pii: S0140-6736(18)31133-4. doi: 10.1016/S0140-6736(18)31133-4. (Original Study)
Read 1902 times
 2.Reduced-dose direct oral anticoagulants in the extended treatment of venous thromboembolism: a systematic review and meta-analysis.
J Thromb Haemost. 2018 Jul;16(7):1288-1295. doi: 10.1111/jth.14156. Epub 2018 Jun 17. (Systematic Review)
Read 1848 times
 3.Effect of Alteplase vs Aspirin on Functional Outcome for Patients With Acute Ischemic Stroke and Minor Nondisabling Neurologic Deficits: The PRISMS Randomized Clinical Trial.
JAMA. 2018 Jul 10;320(2):156-166. doi: 10.1001/jama.2018.8496. (Original Study)
Read 1618 times

* by physicians around the world in the past 30 days
** excluding articles with relevance or newsworthiness scores below 6 (on a scale of 1 to 7)