See what CanVECTOR members are publishing to advance the field of venous thromboembolism
Publications since 2016 that are linked to venous thromboembolism and/or anticoagulant therapy

Publications for Deborah Siegal

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#	PubMedId	Deleted	Publication
	39268016	0	Ladak R, Sementilli M, Calandra J, et al. Physician practice patterns on the use of inferior vena cava filters in venous thromboembolism. Res Pract Thromb Haemost. 2024 Aug 5;8(6):102540. doi: 10.1016/j.rpth.2024.102540. eCollection 2024 Aug.
	39029742	0	Levy JH, Shaw JR, Castellucci LA, et al. Reversal of direct oral anticoagulants: guidance from the SSC of the ISTH. J Thromb Haemost. 2024 Jul 17:S1538-7836(24)00426-4. doi: 10.1016/j.jtha.2024.07.009.
	38826076	0	Field TS, Lindsay MP, Wein T, et al. Canadian Stroke Best Practice Recommendations, 7(th) Edition: Cerebral Venous Thrombosis, 2024. Can J Neurol Sci. 2024 Jun 3:1-57. doi: 10.1017/cjn.2024.269.
	38823454	0	Carlin S, Cuker A, Gatt A, et al. Anticoagulation for Stroke Prevention in Atrial Fibrillation and Treatment of Venous Thromboembolism and Portal Vein Thrombosis in Cirrhosis: Guidance from the SSC of the ISTH. J Thromb Haemost. 2024 May 30:S1538-7836(24)00311-8. doi: 10.1016/j.jtha.2024.05.023.
	38620086	0	Siegal DM, Forbes N, Eikelboom J, et al. The Efficacy and Safety of Andexanet Alfa in Patients With Acute Gastrointestinal Bleeding While Taking Factor Xa Inhibitors: An ANNEXA-4 Subanalysis. Circulation. 2024 Apr 16;149(16):1315-1318. doi: 10.1161/CIRCULATIONAHA.123.066933. Epub 2024 Apr 15.
	38548736	0	Tran A, Fernando SM, Rochwerg B, et al. Prognostic Factors Associated with Venous Thromboembolism Following Traumatic Injury: A Systematic Review and Meta-Analysis. J Trauma Acute Care Surg. 2024 Mar 29. doi: 10.1097/TA.0000000000004326.
	38324588	0	Lun R, Siegal D, Ramsay T, et al. Synthetic data in cancer and cerebrovascular disease research: A novel approach to big data. PLoS One. 2024 Feb 7;19(2):e0295921. doi: 10.1371/journal.pone.0295921. eCollection 2024.
	38266535	0	Gunka B, Mackenzie D, Hughes T, et al. Pharmacokinetics of direct oral anticoagulants after bariatric surgery: A retrospective cohort study. Thromb Res. 2024 Jan 17;235:15-17. doi: 10.1016/j.thromres.2024.01.007.
	38233019	0	Bejjani A, Khairani CD, Assi A, et al. When Direct Oral Anticoagulants Should Not Be Standard Treatment: JACC State-of-the-Art Review. J Am Coll Cardiol. 2024 Jan 23;83(3):444-465. doi: 10.1016/j.jacc.2023.10.038.
	38097360	0	Siegal DM, Verbrugge FH, Martin AC, et al. Country and health expenditure are major predictors of withholding anticoagulation in atrial fibrillation patients at high risk of stroke. Open Heart. 2023 Dec 14;10(2):e002506. doi: 10.1136/openhrt-2023-002506.
	37910528	0	Shaw JR, James T, Douxfils J, et al. Thrombin generation, bleeding and hemostasis in humans: Protocol for a scoping review of the literature. PLoS One. 2023 Nov 1;18(11):e0293632. doi: 10.1371/journal.pone.0293632. eCollection 2023.
	37850360	0	Lun R, Cerasuolo JO, Carrier M, et al. Previous Ischemic Stroke Significantly Alters Stroke Risk in Newly Diagnosed Cancer Patients. Stroke. 2023 Oct 18. doi: 10.1161/STROKEAHA.123.042993.
	36971601	0	Eikelboom R, Whitlock RP, Muzaffar R, et al. Direct oral anticoagulants versus vitamin K antagonists in the first 3 months after bioprosthetic valve replacement: a systematic review and meta-analysis. Eur J Cardiothorac Surg. 2023 Mar 27:ezad110. doi: 10.1093/ejcts/ezad110.
	36940444	0	Wang TY, Wahed AS, Morris A, et al. Effect of Thromboprophylaxis on Clinical Outcomes After COVID-19 Hospitalization. Ann Intern Med. 2023 Mar 21. doi: 10.7326/M22-3350.
	36858345	0	Schenker C, Marx CE, Kraaijpoel N, et al. Definitions of fatal bleeding in clinical studies evaluating anticoagulant treatment for venous thromboembolism: A scoping review. J Thromb Haemost. 2023 Feb 27:S1538-7836(23)00161-7. doi: 10.1016/j.jtha.2023.02.013.
	36696204	0	Shaw JR, Castellucci LA, Siegal D, et al. DOAC-associated bleeding, hemostatic strategies, and thrombin generation assays - a review of the literature. J Thromb Haemost. 2023 Mar;21(3):433-452. doi: 10.1016/j.jtha.2022.11.029. Epub 2022 Dec 22.
	36696186	0	Caiano LM, Drury T, Zahrai A, et al. Role of statins in the prevention of post-thrombotic syndrome after a deep vein thrombosis event: a systematic review and meta-analysis. J Thromb Haemost. 2022 Dec 22:S1538-7836(22)18246-2. doi: 10.1016/j.jtha.2022.12.008.
	36696183	0	Aziz J, Wang TF, Siegal D, et al. Thrombotic and bleeding outcomes following the perioperative interruption of anticoagulation among patients with nonvalvular atrial fibrillation and active cancer. J Thromb Haemost. 2022 Dec 27:S1538-7836(22)18255-3. doi: 10.1016/j.jtha.2022.12.016.
	36514164	0	Chornenki NLJ, Tritschler T, Stucki F, et al. All-cause mortality after major gastrointestinal bleeding among patients receiving direct oral anticoagulants: a protocol for a systematic review and meta-analysis. Syst Rev. 2022 Dec 13;11(1):269. doi: 10.1186/s13643-022-02146-5.
	36462135	0	Siegal DM, Freedman D, Ansell J. Urgent procedures or surgeries in patients receiving oral anticoagulants: a systematic literature review. J Thromb Thrombolysis. 2023 Feb;55(2):197-202. doi: 10.1007/s11239-022-02739-w. Epub 2022 Dec 3.
	36213364	0	Siegal DM, Leong DP. Evaluating Anticoagulant Strategies for Atrial Fibrillation in Patients With Cancer: Challenges and Opportunities. JACC CardioOncol. 2022 Sep 20;4(3):351-353. doi: 10.1016/j.jaccao.2022.08.005. eCollection 2022 Sep.
	35918731	0	Holbrook AM, Vidug K, Yoo L, et al. Coordination of Oral Anticoagulant Care at Hospital Discharge (COACHeD): protocol for a pilot randomised controlled trial. Pilot Feasibility Stud. 2022 Aug 2;8(1):166. doi: 10.1186/s40814-022-01130-z.
	35814801	0	Ariens RA, Hunt BJ, Agbani EO, et al. Illustrated State-of-the-Art Capsules of the ISTH 2022 Congress. Res Pract Thromb Haemost. 2022 Jul 6;6(5):e12747. doi: 10.1002/rth2.12747. eCollection 2022 Jul.
	35748885	0	Cuker A, Tseng EK, Schunemann HJ, et al. American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19: March 2022 update on the use of anticoagulation in critically ill patients Blood Adv. 2022 Jun 24. pii: 485690. doi: 10.1182/bloodadvances.2022007940.
	35735219	0	den Exter PL, Woller SC, Robert-Ebadi H, et al. Management of bleeding risk in patients who receive anticoagulant therapy for venous thromboembolism: Communication from the ISTH SSC Subcommittee on Predictive and Diagnostic Variables in Thrombotic Disease. J Thromb Haemost. 2022 Jun 4. doi: 10.1111/jth.15776.
	35697453	0	Wang M, Paterson M, Thabane L, et al. Association of direct oral anticoagulant-proton pump inhibitor cotherapy with adverse outcomes: protocol for a population-based cohort study. BMJ Open. 2022 Jun 13;12(6):e057991. doi: 10.1136/bmjopen-2021-057991.
	35648414	0	Bikdeli B, Zahedi Tajrishi F, Sadeghipour P, et al. Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review. JAMA Cardiol. 2022 Jun 1. pii: 2793119. doi: 10.1001/jamacardio.2022.1292.
	35577626	0	Nicholson M, Goubran H, Chan N, et al. No apparent association between mRNA COVID-19 vaccination and venous thromboembolism. Blood Rev. 2022 May 11:100970. doi: 10.1016/j.blre.2022.100970.
	35503027	0	Cuker A, Tseng EK, Nieuwlaat R, et al. American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19: January 2022 update on the use of therapeutic-intensity anticoagulation in acutely ill patients. Blood Adv. 2022 May 3. pii: 485124. doi: 10.1182/bloodadvances.2022007561.
	34727173	0	Cuker A, Tseng EK, Nieuwlaat R, et al. American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19: July 2021 update on post-discharge thromboprophylaxis. Blood Adv. 2021 Nov 2. pii: 477753. doi: 10.1182/bloodadvances.2021005945.
	34636806	0	Tran A, Fernando SM, Rochwerg B, et al. Prognostic Factors Associated With Development of Venous Thromboembolism in Critically Ill Patients-A Systematic Review and Meta-Analysis. Crit Care Med. 2021 Oct 12. pii: 00003246-900000000-95047. doi: 10.1097/CCM.0000000000005382.
	34587197	0	Holbrook A, Wang M, Swinton M, et al. Barriers and facilitators for optimizing oral anticoagulant management: Perspectives of patients, caregivers, and providers. PLoS One. 2021 Sep 29;16(9):e0257798. doi: 10.1371/journal.pone.0257798. eCollection 2021.
	34474482	0	Cuker A, Tseng EK, Nieuwlaat R, et al. American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19: May 2021 update on the use of intermediate-intensity anticoagulation in critically ill patients. Blood Adv. 2021 Oct 26;5(20):3951-3959. doi: 10.1182/bloodadvances.2021005493.
	34403852	0	Fernando SM, Mathew R, Munshi L, et al. Media portrayals of pulmonary embolism. Thromb Res. 2021 Oct;206:52-54. doi: 10.1016/j.thromres.2021.08.006. Epub 2021 Aug 11.
	34399433	0	Wang TF, Carrier M, Fournier K, et al. Oral Anticoagulant Use in Patients with Morbid Obesity: A Systematic Review and Meta-Analysis. Thromb Haemost. 2021 Aug 16. doi: 10.1055/a-1588-9155.
	34387202	0	Tran A, Fernando SM, Carrier M, et al. Efficacy and Safety of Low Molecular Weight Heparin Versus Unfractionated Heparin for Prevention of Venous Thromboembolism in Trauma Patients: A Systematic Review and Meta-Analysis. Ann Surg. 2021 Aug 13. pii: 00000658-900000000-93329. doi: 10.1097/SLA.0000000000005157.
	34351722	0	Goligher EC, Bradbury CA, McVerry BJ, et al. Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19. N Engl J Med. 2021 Aug 26;385(9):777-789. doi: 10.1056/NEJMoa2103417. Epub 2021 Aug 4.
	34351721	0	Lawler PR, Goligher EC, Berger JS, et al. Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19. N Engl J Med. 2021 Aug 26;385(9):790-802. doi: 10.1056/NEJMoa2105911. Epub 2021 Aug 4.
	34273241	0	Xu Y, Siegal DM. Anticoagulant-associated gastrointestinal bleeding: Framework for decisions about whether, when and how to resume anticoagulants. J Thromb Haemost. 2021 Oct;19(10):2383-2393. doi: 10.1111/jth.15466. Epub 2021 Jul 29.
	34027291	0	Ikesaka R, Siegal D, Mallick R, et al. Thromboprophylaxis with rivaroxaban in patients with malignancy and central venous lines (TRIM-Line): A two-center open-label pilot randomized controlled trial. Res Pract Thromb Haemost. 2021 May 5;5(4):e12517. doi: 10.1002/rth2.12517. eCollection 2021 May.
	33649169	0	Little DHW, Sutradhar R, Cerasuolo JO, et al. Rates of rebleeding, thrombosis and mortality associated with resumption of anticoagulant therapy after anticoagulant-related bleeding. CMAJ. 2021 Mar 1;193(9):E304-E309. doi: 10.1503/cmaj.201433.
	33634446	0	Milling TJ Jr, King B, Yue P, et al. Restart of Anticoagulant Therapy and Risk of Thrombosis, Rebleeding, and Death after Factor Xa Inhibitor Reversal in Major Bleeding Patients. Thromb Haemost. 2021 Aug;121(8):1097-1106. doi: 10.1055/a-1400-6159. Epub 2021 Feb 25.
	33560401	0	Cuker A, Tseng EK, Nieuwlaat R, et al. American Society of Hematology 2021 guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19. Blood Adv. 2021 Feb 9;5(3):872-888. doi: 10.1182/bloodadvances.2020003763.
	33351119	0	Siegal DM, Barnes GD, Langlois NJ, et al. A toolkit for the collection of thrombosis-related data elements in COVID-19 clinical studies. Blood Adv. 2020 Dec 22;4(24):6259-6273. doi: 10.1182/bloodadvances.2020003269.
	33078911	0	Xu Y, Siegal DM, Anand SS. Ethnoracial variations in venous thrombosis: Implications for management, and a call to action. J Thromb Haemost. 2021 Jan;19(1):30-40. doi: 10.1111/jth.15140. Epub 2020 Nov 20.
	33000892	0	Little DHW, Robertson T, Douketis J, et al. Management of antithrombotic therapy after gastrointestinal bleeding: A mixed methods study of health-care providers. J Thromb Haemost. 2021 Jan;19(1):153-160. doi: 10.1111/jth.15111. Epub 2020 Oct 21.
	32762455	0	Siegal DM, Gross PL. Narrowing in on the True Rate of Venous Thromboembolism in Hospitalized Patients With COVID-19 Disease. Arterioscler Thromb Vasc Biol. 2020 Sep;40(9):1958-1960. doi: 10.1161/ATVBAHA.120.314977. Epub 2020 Jul 30.
	32680646	0	Tomaselli GF, Mahaffey KW, Cuker A, et al. 2020 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2020 Aug 4;76(5):594-622. doi: 10.1016/j.jacc.2020.04.053. Epub 2020 Jul 14.
	32146068	0	Siegal DM, Healey JS. Shared Decision-Making for Anticoagulation in Atrial Fibrillation: Do Physicians Really Listen? Can J Cardiol. 2020 Apr;36(4):459-461. doi: 10.1016/j.cjca.2019.11.008. Epub 2019 Nov 15.
	32142099	0	Siegal DM, Eikelboom JW, Lee SF, et al. Variations in incidence of venous thromboembolism in low-, middle-, and high-income countries. Cardiovasc Res. 2021 Jan 21;117(2):576-584. doi: 10.1093/cvr/cvaa044.
	31808849	0	Kimpton M, Siegal DM. Evidence-Based Minireview: Mortality and thrombosis in patients receiving prothrombin complex concentrates or andexanet alfa for the management of direct oral factor Xa inhibitor-associated major bleeding. Hematology Am Soc Hematol Educ Program. 2019 Dec 6;2019(1):204-208. doi: 10.1182/hematology.2019000074.
	31808835	0	Siegal DM. What we have learned about direct oral anticoagulant reversal. Hematology Am Soc Hematol Educ Program. 2019 Dec 6;2019(1):198-203. doi: 10.1182/hematology.2019000072.
	31806700	0	Verbrugge FH, Martin AC, Siegal D, et al. Impact of oral anticoagulation in patients with atrial fibrillation at very low thromboembolic risk. Heart. 2020 Jun;106(11):845-851. doi: 10.1136/heartjnl-2019-315873. Epub 2019 Dec 5.
	31668083	0	Abdulrehman J, Eikelboom JW, Siegal DM. Andexanet alfa for reversal of factor Xa inhibitors: a critical review of the evidence. Future Cardiol. 2019 Nov;15(6):395-404. doi: 10.2217/fca-2019-0038. Epub 2019 Oct 31.
	31614388	0	Bikdeli B, Jimenez D, Garcia-Tsao G, et al. Venous Thromboembolism in Patients with Liver Cirrhosis: Findings from the RIETE (Registro Informatizado de la Enfermedad TromboEmbolica) Registry. Semin Thromb Hemost. 2019 Nov;45(8):793-801. doi: 10.1055/s-0039-1697682. Epub 2019 Oct 15.
	31436045	0	Spyropoulos AC, Brohi K, Caprini J, et al. Scientific and Standardization Committee Communication: Guidance document on the periprocedural management of patients on chronic oral anticoagulant therapy: Recommendations for standardized reporting of procedural/surgical bleed risk and patient-specific thromboembolic risk. J Thromb Haemost. 2019 Nov;17(11):1966-1972. doi: 10.1111/jth.14598. Epub 2019 Aug 22.
	31252313	0	Little D, Siegal DM. Resumption of anticoagulant therapy after anticoagulant-related gastrointestinal bleeding. Thromb Res. 2019 Aug;180:86. doi: 10.1016/j.thromres.2019.06.003. Epub 2019 Jun 13.
	31100632	0	Chornenki NLJ, Um KJ, Mendoza PA, et al. Risk of venous and arterial thrombosis in non-surgical patients receiving systemic tranexamic acid: A systematic review and meta-analysis. Thromb Res. 2019 Jul;179:81-86. doi: 10.1016/j.thromres.2019.05.003. Epub 2019 May 5.
	30730782	0	Connolly SJ, Crowther M, Eikelboom JW, et al. Full Study Report of Andexanet Alfa for Bleeding Associated with Factor Xa Inhibitors. N Engl J Med. 2019 Apr 4;380(14):1326-1335. doi: 10.1056/NEJMoa1814051. Epub 2019 Feb 7.
	30597497	0	De Caterina R, Ageno W, Agnelli G, et al. The Non-Vitamin K Antagonist Oral Anticoagulants in Heart Disease: Section V-Special Situations. Thromb Haemost. 2019 Jan;119(1):14-38. doi: 10.1055/s-0038-1675816. Epub 2018 Dec 31.
	29324333	0	Shaw JR, Castellucci L, Siegal D, et al. Management of direct oral anticoagulant associated bleeding: Results of a multinational survey. Thromb Res. 2018 Mar;163:19-21. doi: 10.1016/j.thromres.2018.01.008. Epub 2018 Jan 5.
	29203195	0	Tomaselli GF, Mahaffey KW, Cuker A, et al. 2017 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants: A Report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways. J Am Coll Cardiol. 2017 Dec 19;70(24):3042-3067. doi: 10.1016/j.jacc.2017.09.1085. Epub 2017 Dec 1.
	29136562	0	Chai-Adisaksopha C, Iorio A, Hillis C, et al. Warfarin resumption following anticoagulant-associated intracranial hemorrhage: A systematic review and meta-analysis. Thromb Res. 2017 Dec;160:97-104. doi: 10.1016/j.thromres.2017.11.001. Epub 2017 Nov 11.
	28722597	0	Martin L, Burute N, Haider E, et al. Occult Amebic Liver Abscess as Cause of Extensive Inferior Vena Cava and Hepatic Vein Thrombosis. Am J Trop Med Hyg. 2017 Oct;97(4):1214-1217. doi: 10.4269/ajtmh.17-0258. Epub 2017 Jul 19.
	28632284	0	Chu DK, Hillis CM, Leong DP, et al. Benefits and Risks of Antithrombotic Therapy in Essential Thrombocythemia: A Systematic Review. Ann Intern Med. 2017 Aug 1;167(3):170-180. doi: 10.7326/M17-0284. Epub 2017 Jun 27.
	28546438	0	Burnett A, Siegal D, Crowther M. Specific antidotes for bleeding associated with direct oral anticoagulants. BMJ. 2017 May 25;357:j2216. doi: 10.1136/bmj.j2216.
	27637548	0	Samuelson BT, Cuker A, Siegal DM, et al. Laboratory Assessment of the Anticoagulant Activity of Direct Oral Anticoagulants: A Systematic Review. Chest. 2017 Jan;151(1):127-138. doi: 10.1016/j.chest.2016.08.1462. Epub 2016 Sep 13.
	27573206	0	Connolly SJ, Milling TJ Jr, Eikelboom JW, et al. Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors. N Engl J Med. 2016 Sep 22;375(12):1131-41. doi: 10.1056/NEJMoa1607887. Epub 2016 Aug 30.
	27488143	0	Chai-Adisaksopha C, Hillis C, Siegal DM, et al. Prothrombin complex concentrates versus fresh frozen plasma for warfarin reversal. A systematic review and meta-analysis. Thromb Haemost. 2016 Oct 28;116(5):879-890. doi: 10.1160/TH16-04-0266. Epub 2016 Aug 4.
	26637757	0	Siegal DM, Savage WJ. Plasma versus prothrombin complex concentrate for warfarin-associated major bleeding: a systematic review. Hematology Am Soc Hematol Educ Program. 2015;2015:448-53. doi: 10.1182/asheducation-2015.1.448.
	26637710	0	Cuker A, Siegal D. Monitoring and reversal of direct oral anticoagulants. Hematology Am Soc Hematol Educ Program. 2015;2015:117-24. doi: 10.1182/asheducation-2015.1.117.
	26559317	0	Siegal DM, Curnutte JT, Connolly SJ, et al. Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity. N Engl J Med. 2015 Dec 17;373(25):2413-24. doi: 10.1056/NEJMoa1510991. Epub 2015 Nov 11.
	25586208	0	Siegal DM. Managing target-specific oral anticoagulant associated bleeding including an update on pharmacological reversal agents. J Thromb Thrombolysis. 2015 Apr;39(3):395-402. doi: 10.1007/s11239-015-1167-9.
	25403952	0	Chan NC, Siegal D, Lauw MN, et al. A systematic review of contemporary trials of anticoagulants in orthopaedic thromboprophylaxis: suggestions for a radical reappraisal. J Thromb Thrombolysis. 2015 Aug;40(2):231-9. doi: 10.1007/s11239-014-1153-7.