See what CanVECTOR members are publishing to advance the field of venous thromboembolism
Publications since 2016 that are linked to venous thromboembolism and/or anticoagulant therapy

Publications for Ishac Nazy

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#	PubMedId	Deleted	Publication
	39551436	0	Warkentin TE, Geerts W, Sheppard JI, et al. High-dose IVIG and usual heparin anticoagulation for urgent cardiac surgery in a patient with severe autoimmune HIT. J Thromb Haemost. 2024 Nov 15:S1538-7836(24)00687-1. doi: 10.1016/j.jtha.2024.10.035.
	39523606	0	Arnold DM, Pare G, Nazy I. Genetic predisposition to vaccine-induced immune thrombotic thrombocytopenia. Br J Haematol. 2025 Jan;206(1):387-388. doi: 10.1111/bjh.19885. Epub 2024 Nov 10.
	38762021	0	Vayne C, Rollin J, Clare R, et al. THE USE OF 1E12, A MONOCLONAL ANTI-PLATELET FACTOR 4 ANTIBODY TO IMPROVE THE DIAGNOSIS OF VACCINE-INDUCED IMMUNE THROMBOTIC THROMBOCYTOPENIA. J Thromb Haemost. 2024 May 16:S1538-7836(24)00287-3. doi: 10.1016/j.jtha.2024.05.005.
	38733981	0	Bissola AL, Zhang Y, Cranstone M, et al. Evaluating Diagnostic Algorithms for Heparin-Induced Thrombocytopenia using Two Combined Automated Rapid Immunoassays. Semin Thromb Hemost. 2024 May 11. doi: 10.1055/s-0044-1786749.
	38503600	0	Schulman S, Arnold DM, Bradbury CA, et al. 2023 ISTH update of the 2022 ISTH guidelines for antithrombotic treatment in COVID-19. J Thromb Haemost. 2024 Mar 18:S1538-7836(24)00113-2. doi: 10.1016/j.jtha.2024.02.011.
	38467823	0	Yang Y, Du Y, Ivanov D, et al. Molecular architecture and platelet-activating properties of small immune complexes assembled on heparin and platelet factor 4. Commun Biol. 2024 Mar 11;7(1):308. doi: 10.1038/s42003-024-05982-4.
	38398325	0	Zhang Y, Bissola AL, Treverton J, et al. Vaccine-Induced Immune Thrombotic Thrombocytopenia: Clinicopathologic Features and New Perspectives on Anti-PF4 Antibody-Mediated Disorders. J Clin Med. 2024 Feb 9;13(4):1012. doi: 10.3390/jcm13041012.
	38149432	0	Gabarin N, Hack M, Revilla R, et al. Hematology in the post-COVID era: spotlight on vaccine-induced immune thrombotic thrombocytopenia and a conceptual framework (the 4P's) for anti-PF4 diseases. Expert Rev Hematol. 2023 Dec 27:1-7. doi: 10.1080/17474086.2023.2298333.
	38142844	0	Moroniti JJ, Vrbensky JR, Nazy I, et al. Targeted ADAMTS-13 replacement therapy for thrombotic thrombocytopenic purpura. J Thromb Haemost. 2024 Apr;22(4):896-904. doi: 10.1016/j.jtha.2023.11.030. Epub 2023 Dec 22.
	37590457	0	Warkentin TE, Baskin-Miller J, Raybould AL, et al. Adenovirus-Associated Thrombocytopenia, Thrombosis, and VITT-like Antibodies. N Engl J Med. 2023 Aug 10;389(6):574-577. doi: 10.1056/NEJMc2307721.
	37394121	0	Huynh A, Arnold DM, Ivetic N, et al. Antibodies against platelet factor 4 and the risk of cerebral venous sinus thrombosis in patients with vaccine-induced immune thrombotic thrombocytopenia. J Thromb Haemost. 2023 Jun 30:S1538-7836(23)00512-3. doi: 10.1016/j.jtha.2023.06.026.
	37182698	0	Warkentin TE, Arnold DM, Sheppard JI, et al. Investigation of Anti-PF4 versus Anti-PF4/Heparin Reactivities by Fluid-Phase EIA for Four Anti-PF4 Disorders: Classic HIT, Autoimmune HIT, VITT, Spontaneous HIT. J Thromb Haemost. 2023 May 12:S1538-7836(23)00395-1. doi: 10.1016/j.jtha.2023.04.034.
	36798284	0	Yang Y, Du Y, Ivanov D, et al. Molecular architecture and platelet-activating properties of small immune complexes assembled on intact heparin and their possible involvement in heparin-induced thrombocytopenia. bioRxiv. 2023 Feb 11:2023.02.11.528150. doi: 10.1101/2023.02.11.528150. Preprint.
	36574172	0	Venier LM, Clerici B, Bissola AL, et al. Unique features of vaccine-induced immune thrombotic thrombocytopenia; a new anti-platelet factor 4 antibody-mediated disorder. Int J Hematol. 2022 Dec 27:1-8. doi: 10.1007/s12185-022-03516-4.
	36352844	0	Jevtic SD, Arnold DM, Modi D, et al. Vaccine-induced immune thrombotic thrombocytopenia: Updates in pathobiology and diagnosis. Front Cardiovasc Med. 2022 Oct 24;9:1040196. doi: 10.3389/fcvm.2022.1040196. eCollection 2022.
	36351906	0	Buoninfante A, Andeweg A, Baker AT, et al. Understanding thrombosis with thrombocytopenia syndrome after COVID-19 vaccination. NPJ Vaccines. 2022 Nov 9;7(1):141. doi: 10.1038/s41541-022-00569-8.
	35779962	0	Mouta Nunes de Oliveira P, Mendes-de-Almeida DP, Bertollo Gomes Porto V, et al. Vaccine-induced immune thrombotic thrombocytopenia after COVID-19 vaccination: Description of a series of 39 cases in Brazil. Vaccine. 2022 Jun 16. pii: S0264-410X(22)00761-7. doi: 10.1016/j.vaccine.2022.06.014.
	35609563	0	Bissola AL, Daka M, Arnold DM, et al. The clinical and laboratory diagnosis of vaccine-induced immune thrombotic thrombocytopenia. Blood Adv. 2022 Jul 26;6(14):4228-4235. doi: 10.1182/bloodadvances.2022007766.
	35512906	0	Gabarin N, Arnold DM, Nazy I, et al. Treatment of vaccine-induced immune thrombotic thrombocytopenia (VITT). Semin Hematol. 2022 Apr;59(2):89-96. doi: 10.1053/j.seminhematol.2022.03.002. Epub 2022 Mar 7.
	35371058	0	Jevtic SD, Nazy I. The COVID Complex: A Review of Platelet Activation and Immune Complexes in COVID-19. Front Immunol. 2022 Mar 14;13:807934. doi: 10.3389/fimmu.2022.807934. eCollection 2022.
	34663971	0	Kelton JG, Arnold DM, Nazy I. Lessons from vaccine-induced immune thrombotic thrombocytopenia. Nat Rev Immunol. 2021 Dec;21(12):753-755. doi: 10.1038/s41577-021-00642-8.
	34384129	0	Gabarin N, Patterson S, Pai M, et al. Venous Thromboembolism and Mild Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination. Thromb Haemost. 2021 Dec;121(12):1677-1680. doi: 10.1055/a-1585-6182. Epub 2021 Sep 23.
	34233346	0	Huynh A, Kelton JG, Arnold DM, et al. Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia. Nature. 2021 Aug;596(7873):565-569. doi: 10.1038/s41586-021-03744-4. Epub 2021 Jul 7.
	34107198	0	Bourguignon A, Arnold DM, Warkentin TE, et al. Adjunct Immune Globulin for Vaccine-Induced Immune Thrombotic Thrombocytopenia. N Engl J Med. 2021 Aug 19;385(8):720-728. doi: 10.1056/NEJMoa2107051. Epub 2021 Jun 9.
	34018298	0	Nazy I, Sachs UJ, Arnold DM, et al. Recommendations for the clinical and laboratory diagnosis of VITT against COVID-19: Communication from the ISTH SSC Subcommittee on Platelet Immunology. J Thromb Haemost. 2021 Jun;19(6):1585-1588. doi: 10.1111/jth.15341. Epub 2021 May 20.
	33639037	0	Nazy I, Jevtic SD, Moore JC, et al. Platelet-activating immune complexes identified in critically ill COVID-19 patients suspected of heparin-induced thrombocytopenia. J Thromb Haemost. 2021 May;19(5):1342-1347. doi: 10.1111/jth.15283. Epub 2021 Mar 14.
	33387395	0	Rubino JG, Arnold DM, Warkentin TE, et al. A comparative study of platelet factor 4-enhanced platelet activation assays for the diagnosis of heparin-induced thrombocytopenia. J Thromb Haemost. 2021 Apr;19(4):1096-1102. doi: 10.1111/jth.15233. Epub 2021 Feb 19.
	33326124	0	Warkentin TE, Smythe MA, Ali MA, et al. Serotonin-release assay-positive but platelet factor 4-dependent enzyme-immunoassay negative: HIT or not HIT? Am J Hematol. 2021 Mar 1;96(3):320-329. doi: 10.1002/ajh.26075. Epub 2020 Dec 29.
	32864557	0	Koster A, Nazy I, Birschmann IE, et al. High-dose IVIG plus cangrelor platelet "anesthesia" during urgent heparin-CPB in a patient with recent SRA-negative HIT-thrombosis with persisting platelet-activating antibodies. Res Pract Thromb Haemost. 2020 Jul 23;4(6):1060-1064. doi: 10.1002/rth2.12348. eCollection 2020 Aug.
	32788105	0	Huynh A, Arnold DM, Smith JW, et al. The role of fluid-phase immune complexes in the pathogenesis of heparin-induced thrombocytopenia. Thromb Res. 2020 Oct;194:135-141. doi: 10.1016/j.thromres.2020.06.012. Epub 2020 Jun 6.
	32219982	0	Mithoowani S, Cervi A, Shah N, et al. Management of major bleeds in patients with immune thrombocytopenia. J Thromb Haemost. 2020 Jul;18(7):1783-1790. doi: 10.1111/jth.14809. Epub 2020 May 6.
	32167669	0	Warkentin TE, Sheppard JI, Smith JW, et al. Combination of two complementary automated rapid assays for diagnosis of heparin-induced thrombocytopenia (HIT). J Thromb Haemost. 2020 Jun;18(6):1435-1446. doi: 10.1111/jth.14794. Epub 2020 Apr 27.
	32130721	0	Nazy I, Elliott TD, Arnold DM. Platelet factor 4 inhibits ADAMTS13 activity and regulates the multimeric distribution of von Willebrand factor. Br J Haematol. 2020 Aug;190(4):594-598. doi: 10.1111/bjh.16553. Epub 2020 Mar 4.
	31621093	0	Warkentin TE, Nazy I, Sheppard JI, et al. Serotonin-release assay-negative heparin-induced thrombocytopenia. Am J Hematol. 2020 Jan;95(1):38-47. doi: 10.1002/ajh.25660. Epub 2019 Nov 6.
	31050876	0	Warkentin TE, Sheppard JI, Smith JW, et al. Timeline of heparin-induced thrombocytopenia seroconversion in serial plasma samples tested using an automated latex immunoturbidimetric assay. Int J Lab Hematol. 2019 Aug;41(4):493-502. doi: 10.1111/ijlh.13031. Epub 2019 May 3.
	30693813	0	Ivetic N, Arnold DM, Smith JW, et al. A platelet viability assay (PVA) for the diagnosis of heparin-induced thrombocytopenia. Platelets. 2019;30(8):1017-1021. doi: 10.1080/09537104.2018.1562169. Epub 2019 Jan 29.
	30640980	0	Eekels JJM, Althaus K, Bakchoul T, et al. An international external quality assessment for laboratory diagnosis of heparin-induced thrombocytopenia. J Thromb Haemost. 2019 Mar;17(3):525-531. doi: 10.1111/jth.14383. Epub 2019 Feb 20.
	30582672	0	Huynh A, Arnold DM, Kelton JG, et al. Characterization of platelet factor 4 amino acids that bind pathogenic antibodies in heparin-induced thrombocytopenia. J Thromb Haemost. 2019 Feb;17(2):389-399. doi: 10.1111/jth.14369.
	30064975	0	Warkentin TE, Sheppard JI, Linkins LA, et al. High sensitivity and specificity of an automated IgG-specific chemiluminescence immunoassay for diagnosis of HIT. Blood. 2018 Sep 20;132(12):1345-1349. doi: 10.1182/blood-2018-04-847483. Epub 2018 Jul 31.
	29325985	0	Warkentin TE, Arnold DM, Kelton JG, et al. Platelet-Activating Antibodies Are Detectable at the Earliest Onset of Heparin-Induced Thrombocytopenia, With Implications for the Operating Characteristics of the Serotonin-Release Assay. Chest. 2018 Jun;153(6):1396-1404. doi: 10.1016/j.chest.2018.01.001. Epub 2018 Jan 8.
	29172900	0	Huynh A, Arnold DM, Moore JC, et al. Development of a high-yield expression and purification system for platelet factor 4. Platelets. 2018 May;29(3):249-256. doi: 10.1080/09537104.2017.1378808. Epub 2017 Nov 27.
	28391124	0	Warkentin TE, Sheppard JI, Linkins LA, et al. Performance characteristics of an automated latex immunoturbidimetric assay [HemosIL((R)) HIT-Ab(PF4-H)] for the diagnosis of immune heparin-induced thrombocytopenia. Thromb Res. 2017 May;153:108-117. doi: 10.1016/j.thromres.2017.03.010. Epub 2017 Mar 11.
	28369702	0	Staibano P, Arnold DM, Bowdish DM, et al. The unique immunological features of heparin-induced thrombocytopenia. Br J Haematol. 2017 Apr;177(2):198-207. doi: 10.1111/bjh.14603. Epub 2017 Apr 3.